Methadone: Methadose
Methadone is an analgesic compound that is most commonly used to treat heroin/opiate addiction. In addition, the drug may be prescribed for pain relief. Patients prescribed methadone for opiate addiction are considered to be in methadone maintenance. Patients in methadone maintenance are drug tested commonly to ensure they are (1) taking their methadone and (2) not taking heroin/opiates or other drugs.
Drug Class
Trade Names
Methadose, Dolophine, Amidone
Street Names
Effects Of Use
Analgesia, sedation, respiratory depression, coma.
Approximate Detection Time
Urine: 2-4 days

Oral Fluid: NA
Urine Cutoff Levels
Immunoassay (screening): 300 ng/mL

GC/MS (confirmation): 200 ng/mL. Labs are limited by the number of barbiturates they identify on their GC/MS analyses.
Primary Antigen
Methadone. Methadone is eliminated in the urine as parent drug and as metabolites. The metabolites EDDP and EDMP are VERY different in structure from parent methadone, so they do not react with the drug test.
Common Cross-Reactants
No known cross reactants.

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