Propoxyphene (PPX): Darvon
Propoxyphene is a narcotic analgesic structurally related to Methadone; the drug is used for the relief of mild to moderate pain. Propoxyphene is often dosed in combination with Aspirin and Acetaminophen. Although structurally related to methadone, ppx will not cross react on the MD Opiates or Methadone assays.
Drug Class
Narcotic
Trade Names
Darvon, Darvocet
Street Names
Pain Killer
Effects Of Use
Moderately strong analgesic in normal doses. Larger doses can cause sedation, confusion, hallucinations. G.I. side effects, even bleeding, can occur especially when compounded with aspirin.
Approximate Detection Time
Urine: 2-4 days

Oral Fluid: NA
Urine Cutoff Levels
Immunoassay (screening): 300 ng/mL

GC/MS (confirmation): 300-200 ng/mL. Most laboratories will not automatically confirm for Propoxyphene. Propoxyphene-specific confirmation must be requested.
Primary Antigen
Propoxyphene. The assay has an equal affinity to the metabolite nor-propoxyphene.
Common Cross-Reactants
No known cross-reactants


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